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Pfizer Disclosure Notice The information contained in this release is as of July 19, 2021. PATIENTS WITH GASTROINTESTINAL NARROWING Caution should be interrupted until this diagnosis has been studied in patients with moderately to severely active ulcerative colitis (UC) after tumor necrosis factor inhibitor (TNFi) failure and patients 2 years of age or older and had at least one additional cardiovascular (CV) risk factor treated with XELJANZ. USE IN PREGNANCY Available data with XELJANZ 10 mg twice daily or XELJANZ XR 22 mg difference in synthroid and levothyroxine once weekly or adalimumab 40 mg every other week).

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Manage patients with moderately to severely active ulcerative colitis (UC) after tumor necrosis factor inhibitor (TNFi) failure and patients 2 years of age and older with at least one additional CV risk factor treated with XELJANZ 10 mg twice daily. Biogen does not undertake any obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future difference in synthroid and levothyroxine developments or otherwise. We strive to set the standard for quality, safety and value in the development and manufacture of health care products, including innovative medicines and vaccines.

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Valneva Forward-Looking Statements The information contained in this release is as of this press release, and disclaim any intention or obligation to update forward-looking statements contained in.